Advanced Science Program for Independent Research and Engineering (ASPIRE)


ASPIRE is King School’s elite two-year science research program designed to offer hands-on, high-level experiences to King School’s most promising, top-achieving upper school students to better prepare them for a career in research prior to college.
 

Students in this program participate in on and off-campus research opportunities where they receive mentoring, training, and guidance while focusing on their research

 

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Internships and Advanced STEM

The ASPIRE program consists of two main components:

  1. An internship at a renowned laboratory of the student’s choosing to get hands-on experience in the field of modern scientific research.
  2. Enrollment in the Advanced STEM Research course, where students learn how to appropriately communicate their research in both written and oral formats such that students are competitive at local, state, regional, national, and international science fairs and research competitions. With this training, students are also capable of publishing their work in prestigious research journals.

Students intern at their lab placements for the remaining two summers of their time at King for this two-year program. Current and prospective interested students should contact Dr. Victoria Schulman, vschulman@kingschoolct.org, for more information.
 

Content Framed Portrait

Established in 2018 by Margharet, Frank, Bea '15 and William '17 Nash the Advanced Mathematics and Science Study Program endowed fund supports select students with demonstrated ability and interest in achieving true excellence within science, technology, engineering and/or mathematics in global competition preparation, and/or laboratory research experiences.

If you are interested in supporting this opportunity for students, please contact the development office to discuss how your gift can help.

 


Program Timeline

King students are eligible to apply for the ASPIRE program, which spans 2.5 years, in the fall of their sophomore year.

Fall of Sophomore Year
Students begin the program with a pre-internship class, learning how research is conducted, how a typical lab is organized, what the traditional path to a doctorate degree looks like, how to search for and critically read primary research articles, and how to identify research questions from those readings to aid in the design of their future research project.
Summer Before Junior Year
In the summer before junior year, ASPIRE students spend 8-10 weeks working full-time in an R01-level research lab for the first of two summer intensive internships. The Research Project Grant (R-01) is the oldest and most prestigious grant mechanism used by the National Institute of Health (NIH). R-01 labs conduct research at the highest level. The sustained involvement with the same lab over two summers and a school year makes the research mentor’s investment in training the student highly worthwhile, as the student is able to make meaningful contributions to the lab.
Junior Year
Students continue to work in the lab about one day per week during the academic school year to continue moving their projects forward. Students simultaneously enroll in the Advanced STEM Research course at King School, in which they learn how to compose figures of original data, write research manuscripts, and compose and present video and PowerPoint-style oral presentations of their research. During this year, they are also required to enter their work into a variety of research competitions and science fairs at the local, state, and national levels.
Summer Before Senior Year
The junior school year is bookended with a second summer intensive internship in their research lab between the junior and senior years. Once again, students spend 8-10 weeks working full-time in the lab for their second summer intensive research internship, which constitutes the final stage of their lab work experience.
Senior Year
During their senior year, students cease work in the lab to focus their efforts on preparing their applications for college, the Regeneron Science Talent Search, and other science competitions. To aid in this work, students also re-enroll in the Advanced STEM Research course to hone their writing, presentation, and data/science communication skills.

 

At the conclusion of the two-year program, students give their final presentation to the Upper School at the STEM Colloquium in May.

2024-25 School Year Aspire Projects

Parker Hayashi ’25
  • LungSCOPE: A multimodal machine learning-based framework for overall survival prediction in Non-Small Cell Lung Cancer (NSCLC)
  • Memorial Sloan-Kettering Cancer Center, Quaid Morris Lab (New York, NY)
Zach Louizos ’25
  • Production of efficient solar fuels using noncovalent pi-stacked organic frameworks.
  • Yale University, Shu Hu Lab (New Haven, CT)
Maddie Scanlon ’25
  • Determining COVID-19 vaccine outcomes to dispel public fears of general vaccine use and improve overall public health and safety
  • Athena Fellowship (Remote)
Dillon Maltese ’26
  • Creation of a robotic arm to execute various tasks in the operating room to assist surgeons on delicate procedures.
  • Weill Cornell Medical College, Jeffrey Milsom Lab (New York, NY)
Bruno Reinhoefer Ribeiro ’26
  • Adsorption and removal of chemical pollutants using DNA-wrapped carbon nanotubes.
  • New York University, James Canary/Yoel Ohayon Lab (New York, NY)
Vito Scutari ’26
  • Comprehensive assessment and rehabilitation of executive dysfunction from traumatic brain injuries using video game-based therapies.
  • Sacred Heart University, Jordan Tewel Lab (Fairfield, CT)
Lucia Vivanco ’26
  • Understanding the effect of nutrient additives on the growth and performance of Saccharina latissima and Gracilaria mammillaris to repopulate kelp forests and bolster diminishing marine species populations.
  • University of Chicago and the Marine Biological Laboratory, Loretta Roberson Lab (Wood Hole, MA)
Leon Wang ’26
  • Utilizing clinically developed idiopathic pulmonary fibrosis drugs to develop novel treatments for TGFβ-mediated perivascular fibrosis-driven cerebral amyloid angiopathy and Alzheimer’s disease pathology.
  • Mount Sinai Research Hospital, Joel Blanchard Lab (New York, NY)

 

Highlights of ASPIRE

During each academic year, students are required to submit the current state of their research projects to a variety of competitions and conferences as part of the student’s grade in the Advanced STEM Research course. The purpose of participating in high school research competitions and professional research conferences is to provide opportunities for the students to hone their presentation and communication skills, network with professionals who may open more doors of opportunity for the students, and provide an avenue through which students can receive external validation for their work in the form of recognition, prizes, accolades, and scholarships.

Since 2020, King students have competed successfully in every state and regional competition they were qualified to enter. This is the ultimate goal of the course and the research program as a whole.

 

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Student Achievements and Awards

2024 Graduates' Projects
Antonia Kolb
  • Environmental remediation via photocatalysis for partial methane oxidation and oil photodegradation. (Yale Project)
  • DETICKT IT: A machine learning-based application for real-time tick identification and spatiotemporal disease risk assessment. (Independent Work)
  • Yale University, Shu Hu Lab (New Haven, CT) & Independent Work
Layla Shah
  • Gender-related differences in a murine PCSK9 and HFD model of atherosclerosis.
  • Yale University, Schwartz Lab (New Haven, CT)
Ryan Wempen
  • Utilizing ground and space-based sensors to track trajectories of vehicles and dangerous objects and to monitor climate change and environmental issues
  • Massachusetts Institute of Technology, Lincoln Labs: Air, Missile, & Maritime Defense Technology Group/Interceptor & Sensor Technology Group (Lexington, MA)

2023 Graduates' Projects
Gouri Krishnan
  • Reducing energy loss from wasted plastic and lighting inefficiency through a combination of environmentally friendly polymers created from biomass and energy-saving electrochromic windows.
  • Yale University, Shu Hu Lab (New Haven, CT)
Ben Persily
  • Utilizing and optimizing prime editing to target endogenous loci (CFTR & SOX2) and ameliorate genetic disorders in pluripotent stem cells.
  • Memorial Sloan-Kettering Cancer Center, Ting Zhou Lab (New York, NY)
Yuriy Sandmeier
  • Knocking down of the essential 23S rRNA methyltransferase, rv3579c, increases the susceptibility of Mycobacterium tuberculosis to macrolides.
  • Rockefeller University, Jeremy Rock Lab (New York, NY)

2022 Graduates' Projects
Giovanna Armetta
  • Interned at Memorial Sloan-Kettering Cancer Center
  • Researched drosophila melanogaster locomotion, myonuclei size, and myonuclei position are affected by differential gene expression
  • Currently studying at Rochester University
Billy Bernfeld
  • Knocking down of the essential 23S rRNA methyltransferase, rv3579c, increases the susceptibility of Mycobacterium tuberculosis to macrolides.
  • Rockefeller University, Jeremy Rock Lab (New York, NY)
Adam Nomani
  • Interned at the University of New Haven
  • Researched passive thermal energy storage for air conditioning systems utilizing phase change material
  • Currently studying at the University of Pennsylvania
John Russell
  • Interned at Yale University (New Haven, CT)
  • Researched Clustering X-ray absorption spectra of catalytic materials for energy applications
  • Researched Biocement bricks for negative emissions: Electrochemical ocean carbon capture
  • Currently studying at Harvard University

 

2021 Graduates' Projects
Jacob Boyar
  • Interned at Weill Cornell Medical College
  • Researched genes dysregulated in obesity increase the likelihood of breast cancer development
  • Currently studying at Tufts University
Ryan Heaton
  • Interned at Memorial Sloan-Kettering Cancer Center.
  • Researched subtypes of renal cell carcinoma can be accurately classified using convolutional neural networks
  • Currently studying at Dartmouth College
Sammy Hillenmeyer
  • Interned at Yale University
  • Researched temperature dependence of the electrochemical conversion of methane to methanol
  • Researched the electrochemical oxidation of methane in a fuel cell utilizing carbon sequestration
  • Currently studying at Notre Dame University
Nadia Kucher
  • Interned at the Burke Neurological Institute
  • Researched forelimb movement patterns are impacted by the ablation of motor neurons in the caudal forelimb area
  • Researched deep venous intervention surgeries for lower extremities in out-patient offices do not create additional complications compared to hospital setting
  • Currently studying at New York University
Alex Lim
  • Interned at Sacred Heart University
  • Researched using an automated drone and camera system to improve the safety of schools and other populated areas in a cost effective manner
  • Currently studying at Wesleyan University
  • Wafa Nomani
  • Interned at Memorial Sloan-Kettering Cancer Center
  • Researched Feraheme® nanoparticles as a potential treatment for pancreatic cancer
  • Researched Feraheme® works synergistically with several ROS-inducing drugs to induce lipid peroxidation
  • Currently studying at New York University
Joe Winterlich
  • Interned at Weill Cornell Medical College
  • Researched antimicrobial peptides and antibiotics produce bactericidal and bacteriostatic effects on wild-type E. coli
  • Currently studying at Northeastern University

2020 Graduates' Projects
Harry Amadeo
  • Interned at Columbia University (New York, NY)
  • Researched development of an optimum light-activated catalyst for olefin metathesis reactions
  • Researched transition metal compounds are effective burn-rate catalysts in ammonium perchlorate composite propellant
  • Currently studying at Purdue University
Olivia Sheridan
  • Interned at Yale University (New Haven, CT)
  • Researched CRISPR-induced point mutations in the donor sequence greatly decrease the percentage of donor sequence-double strand break encounters during homology search
  • Currently studying at University of Virginia

 

2019 Graduates' Projects
Portia Cummings
  • Interned at Memorial Sloan-Kettering Cancer Center
  • Researched LDH-A Inhibition and the Kynurenine Pathway as possible Approaches for Cancer Therapy
  • Currently studying at Columbia University
Mallory Ehlers
  • Interned at Memorial Sloan-Kettering Cancer Center
  • Researched iron oxide nanoparticles transport medication to cancer tumors more efficiently, effectively, and harmlessly than traditional chemotherapy
  • Brown University
Ashley Xu
  • Interned at Memorial Sloan-Kettering Cancer Center (New York, NY)
  • Researched Renal Cell Carcinoma (RCC) subtyping via random forest using RCC feature histograms
  • Currently studying at Northwestern University

 


As part of the ASPIRE program, working with a real laboratory and helping conduct original research while I am still in high school is beyond my wildest dreams. The future of DNA as a nanomaterial is as extensive as the combinations it can produce, and the opportunity to work with it is now steering my thoughts towards a career in molecular biology.

 

Meet the Director of Science Research

Meet the Director of Science Research
Dr. Victoria Schulman leans on her vast experience in high-level research to coach and mentor students to help them reach their full potential.

Dr. Schulman earned her Ph.D. in Biomedical Sciences from Weill Cornell Medical College and completed her Postdoctoral research training at Yale University School of Medicine. She has 15+ years of research experience, having worked at many prestigious institutions, including the National Institutes of Health (NIH; Bethesda, MD), the Armed Forces Institute of Pathology at Walter Reed Army Medical Center (Washington, DC), Memorial Sloan-Kettering Cancer Center (New York, NY), Weill Cornell Medical College (New York, NY), and Yale University (New Haven, CT). As a researcher, she was well respected in her field. Having published eight research papers, she was an invited speaker at three national/international research conferences and two national symposiums. She also earned numerous accolades for her research, including the William E. Kirwan Junior Investigator Research Award, the Vincent du Vigneaud Award of Excellence, the Golden Key International Scholar Grant, an NIH Research Grant, and she was even the recipient of the Distinguished Student Award for her graduating class at Weill Cornell Medical College and gave the keynote address at graduation.

After changing careers in 2016 to teaching, Dr. Schulman has brought her expertise to the students at King School, where she mentors young, budding scientists and engineers as they pursue their research interests and present their findings and developments at local, state, regional, national, and international science fairs and research competitions. For her mentorship successes, she has been awarded the Junior Science and Humanities Symposium Regional Teacher Award for Excellence in Research Education, the Education 2.0 (Education of the Future) Outstanding Leadership in STEM Education Award, and been named a Distinguished Modern Classroom Educator and Expert Mentor as well as a Regeneron National Teacher of Merit.


Victoria Schulman
Science Faculty, Director of Science Research
vschulman@kingschoolct.org
Mobile: (301) 537-0184
Work: (203) 322 3496, Ext. 3410
 

Sammy Hillenmeyer '21

While I am studying topics in college that are drastically different from the research I did in high school, the skills learned from the ASPIRE experience are still very valuable to my work. Problem-solving, critical thinking, and collaboration are necessities in the field, no matter what major you end up entering. I have designed and built (with my class) a sample 100-foot bridge in an effort to learn about the forces in a suspension bridge and how to most efficiently put it together. It was a very cool and hands-on project, similar to my research in the lab. I declared civil engineering as my major.

 

Portia Cummings '19

 I am a biology major in my final year at Columbia University and applying to medical school this year. Currently, I am conducting research in the Kim lab which investigates therapies to halt blood vessel growth in cancers, a process known as tumor driven angiogenesis. We target factors that destabilize tumor blood vessels and make it more difficult for immune cells to infiltrate and eradicate cancer cells. Through this research, we hope to elucidate the mechanisms underlying tumor driven angiogenesis and increase the efficacy of anti-angiogenic therapies. The ASMR/ASPIRE program introduced me to the field of cancer biology and aided in my early development of many fundamental laboratory skills. This exposure to basic and translational research had a huge impact on my ability to read and present scientific papers as well as comprehending how a research lab operates. It has been essential in determining my future career objectives, and I am very grateful to have had access to this opportunity while at King.”

 

Harry Amadeo '20

Getting a start in ASPIRE and now working in a propulsion lab solidified my passion for the aerospace industry and has made me more excited than ever to start a career in this field. Currently, I am doing undergraduate research at Purdue's Zucrow Propulsion Laboratories. I am working under a DARPA-funded program, in which we are training artificial intelligence to predict rocket propellant characteristics. Instead of running a multitude of tests on one propellant to determine its attributes, an AI could provide a solid baseline for future use. This will allow for time and money to be saved when researching and developing new propellants.

 

 

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